69228

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69228

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2-(Methylsulfonyl)ethyl N-succinimidyl carbonate

purum, ≥98.0% (N)

Synonym:MSC-ONSu, N-[2-(Methylsulfonyl)ethoxycarbonyloxy]succinimide
CAS Number:57903-15-8
Linear Formula:C8H11NO7S
Molecular Weight:265.24
Beilstein Registry Number:6584148
MDL number:MFCD00043142
PubChem Substance ID:24885897

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Description

Other NotesReagent for introducing the 2-(methylsulfonyl)ethoxycarbonyl, MSC, amino protecting group.; The MSC group is stable to acid and to hydrogenolysis, but cleaved by base1,2; Used for the protection of insulin as (MSC)2-insulin3,4

Properties

gradepurum
assay≥98.0% (N)
mp112-114 °C (dec.)
storage temp.2-8°C

Safety

Hazard CodesXi
Risk Statements36/37/38
Safety Statements26-36
WGK Germany3

References

Cited Reference1. G.J. Tesser, I.C. Balvert-Geers Int. J. Pept. Protein Res. 7, 295, (1975) Abstract
 2. R. Geiger et al. Chem. Ber. 108, 2758, (1975)
 3. A. Schuettler, D. Brandenburg Hoppe Seyler's Z. Physiol. Chem. 360, 1721, (1979) Abstract
 4. S. Drewes et al. Hoppe Seyler's Z. Physiol. Chem. 362, 745, (1981)